National Institute of Mental Health
Research objectives
– We aim assess the function of glymphatic brain clearance system as assessed by means of MRI in a pre/post Covid manner
– We will perform biomarker profiling before and after SARS-CoV-2 infection (miRNA, S100B, NSE, NF-L, GFAP, UCH-L1) as the multimodal substrate of the long-COVID syndrome.
– We will focus on the link between the glial-lymphatic brain waste clearance system and subcellular markers of cellular injury as a unifying factor behind long-term sequelae of SARS-CoV-2 neuroinfection.