First Department of Neurology, Faculty of Medicine, Masaryk University and St. Anne’s University Hospital, Brno
Research objectives:
– Determine optimal contact for DBS based on lead location, LFP and structural connectivity.
– Define individual spectral patterns in LFP as a potential input signals for aDBS.
– Evaluate alterations in LFP spectral patterns in longitudinal examination in the context of adverse effects of DBS and disease progression.
– Identification of LFP patterns related to different phenotypes of Parkinson’s disease.